Dermatopathology Cases

Image1 Image2 Image 3 Image4 Case 96 A 55 year old male with an ulcerated nodule on the back of the left arm. Diagnosis

Papillary Eccrine Adenoma Visit: Dermatopathology site Visit: Papillary Eccrine Adenoma Abstract: Papillary eccrine adenoma in association with cutaneous horn. Am J Clin Dermatol. 2007;8(3):179-82. Papillary eccrine adenoma (PEA) is an uncommon sweat gland neoplasm that occurs more frequently on the distal extremities of Black women. Clinically, it appears as a small, isolated, firm, dome-shaped cutaneous nodule. We report two unusual cases of PEA that presented clinically as cutaneous horn. Histologically, both cases showed the typical dermal morphology of PEA with overlying epidermal changes suggestive of human papillomavirus (HPV). However, HPV immunoperoxidase staining and polymerase chain reaction for HPV were negative in both cases. Concurrent occurrence of PEA and HPV-like epidermal changes may be coincidental; however, their co-occurrence may also be related to the environment induced by this adnexal tumor. Whether PEA with verrucous epidermal changes has a different clinical b

Image1 Image2 Image3 Image4 Image5 Case 95 A 45 year old male with a firm nodule on the dorsum of his right hand. Diagnosis

Hypertrophic Lichen Planus Visit: Dermatopathology site [ Related links to clinical images of similar condition: (DermAtlas -JHU.): Image1 ; Image2 ; Image3 ; Image4 ] Abstract: Verrucous squamous cell carcinoma complicating hypertrophic lichen planus : Three case reports and review of the literature. Hautarzt. 2011 Jan;62(1):40-45. Lichen planus is a chronic mucocutaneous T-cell-mediated disease, whose cause is still unknown. The first case of lichen planus that transformed into squamous cell carcinoma was reported in 1903. We present three patients in whom squamous cell carcinomas were identified in chronic lichen planus. The world literature includes at least 91 cases, including our three cases. In an epidemiological study, no significant risk of transformation of cutaneous lichen planus into squamous cell carcinomas was found. In contrast, there is a significantly higher risk of malignant transformation in mucosal lichen planus, so that the WHO had graded mucosal lichen planus a

Image1 Image2 Image3 Image4 Case 94 A 20 year old male with multiple pruritic plaques on the extremities. The lesions have a verrucous appearance. Diagnosis [ Related links to clinical images of similar condition: (DermAtlas -JHU.): Image1 ; Image2 ; Image3 ; Image4 ]