Dermatopathology Cases

Image1 Image2 Image3 Case 85 A 35 year old male with skin lesions. Patient has a history of hematopoietic stem cell transplantation. Diagnosis

Polymorphous Light Eruption Visit: Dermatopathology site Abstracts Polymorphous light eruption.Photodermatol Photoimmunol Photomed.2008 Jun;24(3):155-61. Polymorphous light eruption is the most common photodermatosis, with a prevalence of as high as 10-20% in Western Europe and in the USA. It starts during the second and third decades of life. Although not life-threatening it can severely impair the quality of life, in particular during leisure activities and in outdoors workers. Polymorphous light eruption belongs to the group of so-called idiopathic photodermatoses. This term denotes dermatoses that occur in otherwise healthy individuals from exposure to sunlight or artificial light without the intervention of an exogenous photosensitizing agent. These diseases have two factors in common: they are precipitated by ultraviolet or visible radiation; and their exact pathomechanism remains obscure but is presumably immunologic in nature. Marked papillary dermal edema--an unreliable discr

Image1 Image2 Case 84 Small pruritic papules on the dorsum of the hands and forearms of a 25 year old male. The patient has a history of exposure to bright sunlight for many hours. Answer

Gouty Tophus Visit: Dermatopathology site Asymptomatic nodule on an elderly lady's thumb tip. Hautarzt. 2011 Jan 26. A 71-year-old woman presented with an asymptomatic growing dermal tumor on her thumb. Clinical picture, ultrasound, laboratory investigations and histology were consistent with the diagnosis of gouty tophus. Pathogenesis, risk factors and therapy of tophaceous gout are discussed. Gouty tophus of the upper eyelid. Ophthal Plast Reconstr Surg. 2008 Sep-Oct;24(5):404-6. A 64-year-old man with gout presented with history of an enlarging mass in the left upper eyelid causing mechanical ptosis. The patient underwent excisional biopsy. The histopathologic findings confirmed the diagnosis of gouty tophus of the eyelid. Role of Melanocortin Receptors in the Regulation of Gouty Inflammation. Curr Rheumatol Rep. 2011 Jan 18. Gouty arthritis is a form of acute joint inflammation provoked by joint deposition of urate crystals. Although this acute pathology resolves after a few da

Image1 Image2 Image3 Case 83 Slide for spot diagnosis. Answer