Dermatopathology Cases

Image1 Image2 Image 3 Image4 Image4 Case 62 A 40 year old male with a nodule (2.5cm in size) on the forehead. Answer

Dermatopathology Quiz - Case Index : Case 41 = Fibrous Papule of the Face (Fibrous Papule of the Nose) Case 42 = Lupus Panniculitis (Lupus Profundus) Case 43 = Subcutaneous Panniculitis-like T-Cell Lymphoma Case 44 = Necrobiotic Xanthogranuloma Case 45 = Lymphomatoid Papulosis Case 46 = Hailey-Hailey Disease Case 47 = Porokeratosis of Mibelli Case 48 = Cutaneous Leiomyoma (Piloleiomyoma) Case 49 = Mycobacterium Marinum Infection (Fish Tank Granuloma ; Swimming Pool Granuloma) Case 50 = Cutaneous Herpes Simplex Infection Case 51 = Prurigo Nodularis Case 52 = Acquired Tufted Angioma Case 53 = Merkel Cell Carcinoma Case 54 = Ichthyosis Vulgaris Case 55 = Discoid Lupus Erythematosus Case 56 = Lichen Planus Case 57 = Erythema Multiforme Case 58 = Fixed Drug Eruption Case 59 = Pigmented Spindle Cell Nevus of Reed. Case 60 = Spitz Nevus

Targetoid Hemosiderotic Hemangioma (Hobnail Hemangioma) Visit: Dermatopathology site Visit: Targetoid Hemosiderotic Hemangioma (Hobnail Hemangioma) Abstract: Hobnail hemangiomas (targetoid hemosiderotic hemangiomas) are true lymphangiomas.J Cutan Pathol.2004 May;31(5):362-7. BACKGROUND: Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a small benign vascular tumor of the superficial and mid-dermis. In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial cells (LECs). METHODS: We analyzed 10 hobnail hemangiomas by immunohistochemistry, using the recently described lymphatic endothelial cell marker, D2-40. For comparison, CD31, CD34, and alpha-smooth muscle actin expression were studied in consecutive sections of the paraffin-embedded tissues. RESULTS: In all analyzed vessels, D2-40 labeled exclusively LECs, whereas BECs were consistently negative. In contrast to c

Image1 Image2 Image3 Image4 Case 61 A 45 year old male with a violaceous central papule surrounded by an area of pallor and a brown ring. Answer

Spitz Nevus Visit: Dermatopathology site Visit: Pathology of Spitz Nevus The spitz nevus: review and update.Clin Plast Surg.2010 Jan;37(1):21-33. The Spitz nevus is a relatively common skin lesion in children and is less commonly seen in adults. The lesion is defined by the presence of distinctive-appearing spindle or epithelioid cells on light microscopy in a recognizable nevus-like pattern. Spitz lesions share features with melanoma on light microscopic examination. When Spitz features are atypical or typical features are absent, distinction from melanoma can be difficult. A spectrum of pathology of Spitz lesions can be found from lesions that are benign and typical to lesions that are atypical with melanoma-like features and frank melanoma. There is significant interobserver variation in interpretation of Spitz lesions. The lack of uniformly applied criteria for distinction of light microscopic grades and the confusion in diagnostic terminology demonstrate the difficulty in the pat