Dermatopathology Cases

Fibrous Papule of the Face (Fibrous Papule of the Nose) Visit: Dermatopathology site Abstract: Solitary Oral Fibromas of the Tongue Show Similar Morphologic Features to Fibrous Papule of the Face: A Study of 31 Cases. Am J Dermatopathol. 2010 Apr 24. The morphologic similarities between fibrous papules of the face and multiple oral fibromas were mentioned long ago, mainly in the context of phakomatoses. Both lesions have been considered to be different types of angiofibromas. Nonetheless, this interpretation is not accepted by all authors. We tried to investigate if solitary oral fibromas also share morphologic features with fibrous papules of the face. For this purpose, we designed a retrospective study retrieving 31 fibromas of the tongue from 30 different patients and studied a control group of 20 fibrous papules of the face from 20 different patients. From the oral fibromas, 15 lesions presented as dome shape, whereas 16 lesions presented as polypoid. Lesion size varied between 2 a...

Image1 Image2 Image3 Case 41 A 4 mm dome- shaped flesh coloured papule on the nose of a 45 year old female. Answer

Dermatopathology Case Index : Case 21 = Bowen's Disease Case 22 = Fibroepithelioma of Pinkus Case 23 = Pilomatrixoma (Pilomatricoma ; Calcifying epithelioma of Malherbe) Case 24 = Poroma Case 25 = Clear Cell Acanthoma Case 26 = Glomangioma Case 27 = Sebaceoma Case 28 = Molluscum Contagiosum Case 29 = Pilomatrix Carcinoma Case 30 = Xanthelasma Case 31 = Reticulohistiocytoma Case 32 = Sebaceous Hyperplasia Case 33 = Glomeruloid Hemangioma Case 34 = Bacillary Angiomatosis Case 35 = Chromomycosis (Chromoblastomycosis) Case 36 = Angiolymphoid Hyperplasia with Eosinophilia (Epithelioid Hemangioma) Case 37 = Dermatitis Herpetiformis Case 38 = Trichoblastoma Case 39 = Desmoplastic Melanoma Case 40 = Acute Febrile Neutrophilic Dermatosis or Sweet's Syndrome

Acute Febrile Neutrophilic Dermatosis or Sweet's Syndrome Visit: Dermatopathology site Visit: emedicine article: http://emedicine.medscape.com/article/1122152-overview Abstracts: Sweet's syndrome: an update and review.G Ital Dermatol Venereol. 2009 Oct;144(5):603-12. Sweet's syndrome, or acute neutrophilic dermatosis, is an unusual dermatologic disorder that may serve as a marker of leukemia or lymphoma, other malignancy or another serious systemic disorder. It is characterized by the sudden eruption of tender discrete erythematous nodules or plaques which are sometimes associated with fever, neutrophilic leukocytosis, and a dense dermal infiltrate of mature neutrophils. It may occur as a hypersensitivity reaction with cytokines playing a pivotal role. It may remit after the treatment of an underlying cancer or discontinuation of an offending pharmacologic agent, although it con also resolve spontaneously without therapeutic intervention. The gold standard of treatment is ...

Image1 Image2 Image3 Image4 Case 40 A 52 year old female with fever, an elevated neutrophil count, and tender, dark-red plaques on the upper extremities . Answer