Dermatopathology Cases

Dermatitis Herpetiformis Visit: Dermatopathology site Abstract: Dermatitis herpetiformis. An update of the pathogenesis.Hautarzt. 2009 Aug;60(8):627-30, 632. The multifactorial pathogenesis of dermatitis herpetiformis is reviewed in light of current experimental data. Genetic background, gluten consumption, and abnormal immune and autoimmune reactions are the most important pathogenetic factors, but other agents also participate in the disease development. The predisposing and inducing factors are summarized, while the pathophysiological steps leading to the development of skin symptoms are detailed. Dermatitis herpetiformis. A clinical chameleon.Hautarzt. 2006 Nov;57(11):1021-8; quiz 1029. Celiac disease is a genetically determined bowel disease also influenced by exogenous factors in which exposure to grain components triggers a chronic immune response with intestinal symptoms. Dermatitis herpetiformis represents the cutaneous manifestation of celiac disease. While intense pruri...

Image1 Image2 Image3 Case 37 A 35 year old man with small intensely itchy blisters and papules on both the elbows. The patient has a history of celiac disease. Answer

Angiolymphoid Hyperplasia with Eosinophilia (Epithelioid Hemangioma) Visit: Angiolymphoid hyperplasia with eosinophilia(Epithelioid Hemangioma) Visit: Dermatopathology site Visit: Pathology of Vascular Tumours Abstract: Epithelioid hemangioma (angiolymphoid hyperplasia with eosinophilia) of theorbit: a case report. J Med Case Reports. 2007 Jun 25;1:30. ABSTRACT: BACKGROUND: Angiolymphoid hyperplasia with eosinophilia (ALHE) and Kimura's Disease (KD) share many clinical and histopathological features. Although they were once considered different stages of the same disease, they arenow known to represent separate entities. Recently, ALHE is being called epithelioid hemangioma (EH), a term that better describes the possible neoplastic nature of the entity. CASE PRESENTATION: An eighteen year-old Asian female presented with a three-month history of fluctuating swelling and ptosis of the left upper eyelid. Computed tomography disclosed a distinct homogeneous lesion in the left superior...

Image 1 Image 2 Image 3 Image 4 Case 36 A 32 year old Asian man presenting with a dome-shaped, crusted nodule (3 cm in diameter) on the scalp. Answer

Chromomycosis (Chromoblastomycosis) Visit: Pathology of Chromoblastomycosis(Chromomycosis) ; Visit: Dermatopathology site ; Visit: Infectious Disease Online . Abstract: Difficult mycoses of the skin: advances in the epidemiology and management of eumycetoma, phaeohyphomycosis and chromoblastomycosis.Curr Opin Infect Dis. 2009 Dec;22(6):559-63. PURPOSE OF REVIEW: Eumycetoma, phaeohyphomycosis and chromoblastomycosis are subcutaneous mycoses having in common the fact that they are acquired as a result of penetrating trauma to the skin and may be caused by a large variety of fungi. This article will review recent data regarding the epidemiology and treatment of these infections. RECENT FINDINGS: Recent epidemiologic observations in these mycoses include an increased incidence of phaeohyphomycosis in immunosuppressed patients, the association of polymorphisms in genes involved in innate immunity, the occurrence of eumycetoma caused by Madurella mycetomatis and the nosocomial acquisition of...