Dermatopathology Cases

Molluscum Contagiosum Visit: Molluscum Contagiosum Visit: Dermatopathology site Visit: Infectious Disease Online Abstract: Mollusca contagiosa. From paediatric dermatology to sexually transmitted infection.Hautarzt. 2009 Jun;60(6):472-6. Molluscum contagiosum (MC) is a common cutaneous infection caused by the molluscipox virus (MCV) and can affect both children and adults. Molluscum contagiosum is relatively frequent in children aged 1-5 years old and can be localized almost anywhere on the body, but in adults it is regarded as a sexually transmitted infection (STI). MCV can be transmitted directly from person to person or by autoinoculation. MC in adults characteristically involves the genital area but extragenital appearance can be more typically seen in patients with immunosuppressive conditions, especially in HIV/AIDS. The onset of MC inHIV-positive individuals can be regarded as a part of the immune reconstitution inflammatory syndrome (IRIS). MC probably affects both sexes equall...

Image1 Image2 Image3 Case 28 A 17 year old boy with a pearly white papule on the forehead. Answer

Sebaceoma Visit: Pathology of Sebaceoma Visit: Dermatopathology site Visit: Sebaceous Tumours and Tumour-like Lesions Abstract: Sebaceous lesions and their associated syndromes: part I. J Am Acad Dermatol. 2009 Oct;61(4):549-60; quiz 561-2. Sebaceous neoplasms have long been a source of confusion to dermatologists and pathologists alike. Disagreements regarding nomenclature, classification, and management have been longstanding. Sebaceous lesions represent a broad spectrum of interesting entities that range from hamartomas, hyperplasias, and benign tumors to highly malignant neoplasms. This article discusses the clinical and pathologic features of sebaceous hyperplasia, nevus sebaceous of Jadassohn, sebaceous adenoma, seboacanthoma, sebaceous epithelioma, sebaceoma, mantleoma, basal cell carcinoma with sebaceous differentiation, sebomatricoma(sebomatrixoma), and sebaceous carcinoma. Controversies regarding these lesionswill be explored, and any relationship with Muir-Torre syndrome wil...

Image1 Image2 Image3 Image4 Case 27 A 40 year old male with a solitary nodule (2 cm in diameter) on the left side of the face. Answer

Glomangioma Visit: Pathology of Glomus Tumour Visit: Dermatopathology site Visit: Vascular Tumor Abstract: Sclerotic Glomus Tumor. Am J Dermatopathol. 2009 Oct 30. We report an unusual histopathological variant of a glomus tumor that arose in a peculiar topographic site, a sclerotic glomus tumor. Unlike conventional glomus tumors or glomangiomas that have a loose fibrous stroma with variable hyaline and myxoid changes, the case reported herein had a diffuse, hyalinized, sclerotic stroma. A further difference was that the majority of glomus tumors and glomangiomas occur in the subungual area, trunk, or extremities, whereas the present tumor occurred on the ear. Due to the peculiar histological features and location, other tumors were considered in the differential diagnosis to include Merkel cell carcinoma, primitive neuroectodermal tumor, and small cell melanoma. This article illustrates a unique variant of a glomus tumor, which to our knowledge has not been previously described. Local...