Dermatopathology Cases

Image1 Image2 Image3 Case 75 A 52 year old man with a solitary,well-demarcated asymptomatic, brown-red plaque on the face. Answer

Atrophie Blanche (Livedoid Vasculopathy) Visit: Dermatopathology site Abstract: Livedoid vasculopathy as a coagulation disorder. Autoimmun Rev. 2010 Dec 22. Livedoid vasculopathy is an occlusive cutaneous disease of the dermal vessels with pauci-inflammatory or non-inflammatory histopathology findings. It is characterized by the presence of macules or papules, erythemato-purpuric lesions located on the legs, especially on the ankles and feet, which produce ulcerations that are intensely painful and originate ivory atrophic scars called "atrophie blanche". In this review article, studies on LV from the literature are analyzed, and their etiopathogenic associations, particularly those related to the thrombophilic states, as well as the pathologic findings and therapeutic approaches applied in the difficult clinical management of these cases, are evaluated. Livedoid vasculopathy with underlying subcutaneous necrotizing venulitis in an asymptomatic hepatitis B viru

Image1 Image2 Image3 Case 74 A 55 year old woman, with telangiectatic purpuric papules and painful ulcers on the lower part of the legs - mainly around the ankles and dorsum of the feet. Answer

Histochemistry : Methenamine silver stain shows Histoplasma capsulatum fungi. Cutaneous Histoplasmosis Visit: Dermatopathology site Visit : Pathology of Histoplasmosis Abstract: Histoplasmosis Presenting as a Cutaneous Malignancy of the Eyelid. Ophthal Plast Reconstr Surg. 2010 Sep 20. Cutaneous histoplasmosis is an uncommon infection and can occur as a primary infection. A manifestation imitating a cutaneous neoplasm is rare, and eyelid involvement is rarer still. The authors report a case of histoplasmosis that presented as an ulcerated lesion on the lower eyelid margin that clinically resembled a basal cell carcinoma. Given its worldwide distribution, it is important to include this disease in the differential diagnosis of nonhealing eyelid lesions. Biopsy and tissue culture are paramount to establishing the diagnosis. This case describes a rare presentation of histoplasmosis on the eyelid and highlights the importance of histopathologic evaluation. Primary Cutaneous Histoplasmosis

Image1 Image2 Image3 Case 73 Spot diagnosis Answer